IMO the whole idea of this class is that your scenario should be pretty even.
Maybe I read the question wrong, but I think Mike is asking if a nationally competitive car and driver should run head-to-head against a regionally competitive car and driver. And the answer is yes?
I am but one small voice in the whole conversation of NASA weights and plates, but in my opinion you will never equalize 'national' and 'regional' prep and talent levels. That is one element that makes it difficult to read the tea leaves of race results and draw any firm conclusions.
However, I do believe that the rules can (and likely should) be tweaked by examining the Traqmate data, race results, prep levels, talent levels, etc.
And as a highly unpaid NASA volunteer, that opinion carries as much value as you would expect.